Research finds 'Achilles heel' for aggressive prostate cancer

Researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology. Experiments in mice and with human cells showed that blocking this stress response with an experimental drug causes treatment-resistant cancer cells to self-destruct while leaving normal cells unaffected.
Source: Science Daily

Virulence switch in 'Iraqibacter': potential Achilles heel?

Microbiologists have identified a component of a genetic switch, which they call a potential ‘Achilles’ heel,’ for a type of bacteria often associated with wounded warriors. The switch makes it possible for Acinetobacter baumannii to change between a virulent, hardy form and an avirulent form that is better at surviving at lower temperatures outside a host. Defining the switch could map out targets for new antibiotics.
Source: Science Daily

The deep past of megafires, big data’s Achilles heel and behind the scenes of the March for Science: Books in brief

The deep past of megafires, big data’s Achilles heel and behind the scenes of the March for Science: Books in brief

The deep past of megafires, big data’s Achilles heel and behind the scenes of the March for Science: Books in brief, Published online: 11 April 2018; doi:10.1038/d41586-018-04160-x

Barbara Kiser reviews five of the week’s best science picks.
Source: Nature

Russia and China Would Gun for America's Achilles Heel in a War: Satellites

Russia and China Would Gun for America's Achilles Heel in a War: SatellitesCoats noted that both adversary nations are pressing for agreements on preventing the weaponization of space, however the United States intelligence community is suspicious. Russian and Chinese space capabilities are growing rapidly, but moreover, both powers are developing counter-space capabilities to blunt America’s advantage in that domain. “Foreign countries—particularly China and Russia—will continue to expand their space-based reconnaissance, communications, and navigation systems in terms of the numbers of satellites, the breadth of their capability, and the applications for use,” director of national intelligence Dan Coats said in his written testimony before the Senate Armed Services Committee on March 6.


Source: Yahoo! News