Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids, Published online: 03 October 2018; doi:10.1038/s41586-018-0578-0

Cultures grown from small aggregates of mouse embryonic stem cells can be induced to organize spatial and temporal patterns of gene expression that parallel those of the early embryo, offering a potentially useful system for studying early development.
Source: Nature

Inspectors Find Nooses in Cells at Immigration Detention Facility

  1. Inspectors Find Nooses in Cells at Immigration Detention Facility  New York Times
  2. Hudson County Wants to Stop Holding ICE Detainees. Where Will They Go?  WNYC
  3. Surprise Inspection of ICE Facility Reveals Nooses in Cells, Improper Discipline  GovExec.com
  4. rep lieu statement following oversight visit to immigration detention facilities – Congressman Ted Lieu  Congressman Ted Lieu
  5. ‘We don’t feel OK here’: Detainee deaths, suicide attempts and hunger strikes plague California immigration facility  Los Angeles Times
  6. Full coverage


Source: Google News

Keeping our cells stable: A closer look at microtubules

Microtubules help to regulate cell structure throughout our bodies. A group of researchers have used cryo-electron microscopy to shed light on how a certain protein keeps microtubules stable, and regulates microtubule-based transport within cells. The new insights could help to develop medical treatment for diseases such as dementia and heart failure.
Source: Science Daily

How lactoferrin clamps down on free roaming iron ions to stop nefarious effects on cells

What prevents our cells being damaged due to overexposure to iron ions is a protein called lactoferrin, known for its ability to bind tightly to such ions. Researchers used a combined experimental and molecular dynamics simulation to study the changes in the structure of lactoferrin as it binds to iron ions.
Source: Science Daily

Green tea compound helps siRNA slip inside cells

Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss. Although many of these claims still need to be verified in the clinic, an antioxidant in green tea called epigallocatechin gallate (EGCG) appears to have beneficial effects in cells and animals. Now, researchers have found a surprising use for EGCG: sneaking therapeutic RNAs into cells.
Source: Science Daily

Green tea compound helps siRNA slip inside cells

Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss. Although many of these claims still need to be verified in the clinic, an antioxidant in green tea called epigallocatechin gallate (EGCG) appears to have beneficial effects in cells and animals. Now, researchers have found a surprising use for EGCG: sneaking therapeutic RNAs into cells.
Source: Science Daily

Particles surf their own waves, reveal how microbes and cells move through human body

Surf’s up for microbes swimming beside red blood cells. New calculations and experiments model for the first time how spherical particles submerged in gooey liquid travel along a flexible rubber sheet; comparable conditions are common in the human body, such as blood cells flowing through a capillary or the journeys of self-propelled microbes. All these particles, it turns out, catch a wave.
Source: Science Daily

Often-overlooked Natural Killer cells may be key to cancer immunotherapy

Immune checkpoint inhibitors are revolutionizing the treatment of cancer, but new research challenges the central dogma of how these drugs work. This research shows for the first time that often-overlooked immune cells called Natural Killer (NK) cells play a crucial role in responding to checkpoint inhibitors.
Source: Science Daily

Often-overlooked Natural Killer cells may be key to cancer immunotherapy

Immune checkpoint inhibitors are revolutionizing the treatment of cancer, but new research challenges the central dogma of how these drugs work. This research shows for the first time that often-overlooked immune cells called Natural Killer (NK) cells play a crucial role in responding to checkpoint inhibitors.
Source: Science Daily

New technique reveals how Zika virus interacts inside our cells

Scientists have developed a new technique that can determine how viruses interact with a host’s own RNA. As well as providing insight into how viruses direct the host cell to create new virus particles, this technique could allow researchers to design artificial molecules capable of blocking the virus replication process and preventing the virus spreading.
Source: Science Daily

New technique reveals how Zika virus interacts inside our cells

Scientists have developed a new technique that can determine how viruses interact with a host’s own RNA. As well as providing insight into how viruses direct the host cell to create new virus particles, this technique could allow researchers to design artificial molecules capable of blocking the virus replication process and preventing the virus spreading.
Source: Science Daily