Architecture of the human GATOR1 and GATOR1–Rag GTPases complexes

Architecture of the human GATOR1 and GATOR1–Rag GTPases complexes

Architecture of the human GATOR1 and GATOR1–Rag GTPases complexes, Published online: 28 March 2018; doi:10.1038/nature26158

Cryo-electron microscopy and biochemical analyses of the GATOR1 protein complex reveal that two binding modes underpin its ability to regulate Rag GTPases as a GTPase-activating protein for RAGA.
Source: Nature