SIRT6 deficiency results in developmental retardation in cynomolgus monkeys

SIRT6 deficiency results in developmental retardation in cynomolgus monkeys

SIRT6 deficiency results in developmental retardation in cynomolgus monkeys, Published online: 22 August 2018; doi:10.1038/s41586-018-0437-z

A cynomolgus monkey model deficient in SIRT6 protein exhibits severe retardation in prenatal development, in which neuronal differentiation is delayed by activation of the H19 long non-coding RNA.
Source: Nature

New model for predicting neuroblastoma outcomes incorporates early developmental signals

Motivated by a desire to better understand the molecular circuitry underlying neuroblastoma and limitations of current methods for predicting disease progression and outcome, researchers set out to construct a logic-based model incorporating information about developmental signaling pathways implicated in the disease.
Source: Science Daily

Ex-NFL DE Greg Hardy earns UFC developmental contract after 57-second knockout

  1. Ex-NFL DE Greg Hardy earns UFC developmental contract after 57-second knockout  Yahoo Sports
  2. Hardy gets UFC deal after KO in pro MMA debut  ESPN (blog)
  3. Greg Hardy Signs With UFC After Knocking Out Austen Lane to Win Pro MMA Debut  Sports Illustrated
  4. Greg Hardy fight highlights MMA’s troubling history of violence outside the octagon  The Guardian
  5. Full coverage


Source: Google News

Michigan Agrees To Pay $4 Million To Test Flint Kids For Developmental Delays Linked To Lead Poisoning

  1. Michigan Agrees To Pay $4 Million To Test Flint Kids For Developmental Delays Linked To Lead Poisoning  BuzzFeed News
  2. Up to 30000 Flint kids to get screened for effects of lead in their drinking water  USA TODAY
  3. #Flint: State Cuts Off Bottled Water Distribution Claiming Water Quality is Restored  The Root
  4. Flint resident: State’s decision to stop bottled water leaves the most vulnerable in the lurch  Michigan Radio
  5. Full coverage


Source: Google News

Developmental diversification of cortical inhibitory interneurons

Developmental diversification of cortical inhibitory interneurons

Developmental diversification of cortical inhibitory interneurons, Published online: 05 March 2018; doi:10.1038/nature25999

The embryonic emergence of interneuron subtypes in mice is revealed by integrated single-cell transcriptomic analysis along a developmental time course.
Source: Nature