Anti-cancer drugs may hold key to overcoming antimalarial drug resistance

Scientists have found a way to boost the efficacy of the antimalarial drug artemesinin with the help of chemotherapy medicines. Artemisinin works through a ‘double whammy’ attack on the deadly parasite. The drug damages proteins in malaria parasites and clogs the parasite’s waste disposal system, known as the proteasome, which chemo can target.
Source: Science Daily

New nanoparticles wait to release drugs, target infection

Current research shows stimuli-responsive nanoparticles can specifically target infections to simultaneously prevent the spread of bacteria and reduce the inflammation it causes. These microscopic particles are loaded with antibiotic and anti-inflammatory agents which are released when the particles encounter infection in the body. Researchers in the lab of Pharmaceutical Sciences Assistant Professor Zhenjia Wang are looking for a new way to fight sepsis, a systemic inflammatory response that can cause organ failure.
Source: Science Daily