Enantioselective remote <i>meta</i>-C–H arylation and alkylation via a chiral transient mediator

Enantioselective remote meta-C–H arylation and alkylation via a chiral transient mediator

Enantioselective remote <i>meta</i>-C–H arylation and alkylation via a chiral transient mediator, Published online: 18 June 2018; doi:10.1038/s41586-018-0220-1

Remote, enantioselective C–H activation reactions can be achieved by relaying ortho-C–H activation to the meta position, using a chiral norbornene as the mediator.
Source: Nature