New therapeutic opportunity for the treatment of resistant malignant melanoma

Researchers have revealed that malignant melanoma can reprogram their protein synthesis machinery and become addicted to a new family of enzymes that modify transfer RNAs during acquired resistance. The inhibition of these molecules synergies with targeted therapies to produce a strong anti-tumoral effect. These new findings will be key in the development of improved diagnostic tools and melanoma treatment.
Source: Science Daily

Invest in North Korea: money pit or golden opportunity?

Invest in North Korea: money pit or golden opportunity?Donald Trump dangled the carrot of foreign investment in front of North Korean leader Kim Jong Un at their nuclear summit, but analysts say few will want to put money into one of the highest-risk business environments in the world. The US president showed Kim a movie of bright lights, high-speed trains and soaring tower blocks — pitching a future that could be possible if Pyongyang gives up its weapons. Optimists say that with mineral wealth, cheap labour, and a helpful geographical location, the North has huge potential.


Source: Yahoo! News

NASA's Opportunity rover on Mars silenced by intense dust storm. Scientists are 'very concerned'

One of NASA’s robot rovers on Mars has been silenced as a massive dust storm roars across the Martian surface. With its power source — the sun — obscured, the rover Opportunity, “has gone to sleep,” said John Callas, project manager at NASA’s Jet Propulsion Laboratory.

     

 

 


Source: USA Today

Scott Pruitt had aide ask about Chick-fil-A "business opportunity"

  1. Scott Pruitt had aide ask about Chick-fil-A “business opportunity”  CBS News
  2. Emails: Pruitt used EPA aide to inquire about Chick-fil-A business opportunity  CNN
  3. EPA Chief Scott Pruitt Has Racked Up At Least 10 New Scandals In Just The Past Month  HuffPost
  4. Ethics, schmethics, America really needs to know why Scott Pruitt wanted a used Trump hotel mattress  Los Angeles Times
  5. Low-Rent Grifter Scott Pruitt Proves No Con Is Too Small  Vanity Fair
  6. Full coverage


Source: Google News

Emails: Pruitt used EPA aide to inquire about Chick-fil-A business opportunity

  1. Emails: Pruitt used EPA aide to inquire about Chick-fil-A business opportunity  CNN
  2. Scott Pruitt Sought ‘Business Opportunity’ With Chick-fil-A While Leading EPA  New York Times
  3. Scott Pruitt Reportedly Used His Influence to Try to Get His Wife a Chick-fil-A Franchise  Slate Magazine
  4. Ethics, schmethics, America really needs to know why Scott Pruitt wanted a used Trump hotel mattress  Los Angeles Times
  5. Full coverage


Source: Google News

Scott Pruitt Sought 'Business Opportunity' With Chick-fil-A While Leading EPA

  1. Scott Pruitt Sought ‘Business Opportunity’ With Chick-fil-A While Leading EPA  New York Times
  2. Scott Pruitt asked aide to set up call with Chick-fil-A about wife opening franchise  USA TODAY
  3. Scott Pruitt Reportedly Used His Influence to Try to Get His Wife a Chick-fil-A Franchise  Slate Magazine
  4. Ethics, schmethics, America really needs to know why Scott Pruitt wanted a used Trump hotel mattress  Los Angeles Times
  5. Full coverage


Source: Google News

Israel sees an opportunity to drive a wedge between Iran and Russia in Syria

Israel sees an opportunity to drive a wedge between Iran and Russia in SyriaIsrael is increasingly optimistic that it may be coming close to its longheld goal of driving a wedge between Russia and Iran in Syria, a senior Israeli official said today.  Chagai Tzuriel, director general of the Israeli intelligence ministry, said he believed Russia was growing frustrated with Iran’s presence in Syria and was worried that fighting between Israel and Iran would threaten Moscow’s interests.  “My assessment is that the Russians are interested in stabilising their achievements in Syria,” Mr Tzuriel said. “I think they understand that if the Iranians continue on the present course this will lead to escalation and will blow their plans out of the water.” Israel’s has long said it would not allow Iran to gain a permanent military foothold in Syria. Israeli forces have carried out increasingly intense strikes against Iranian targets in Syria in recent weeks and in the process have inflicted serious damage on the Assad regime’s air defences.  Mr Tzuriel said he believed that the Israeli strikes – combined with America’s withdrawal from the Iran nuclear agreement and economic discontent within Iran – were fueling tensions between Iran and its Russian and Syrian allies.   “I think this is a moment pregnant with opportunity. My assessment is that the situation we’re in is an opportune moment to try to change fundamentally the strategic situation,” he said.  Israel hopes that Vladimir Putin (left) and Bashar al-Assad will lose patience with Iran  Credit: MIKHAIL KLIMENTYEV/AFP/Getty Images Mr Tzuriel spoke as unconfirmed reports emerged that the Syrian regime’s air force was trying to expel Iranian troops from its airbases because they were such a frequent target of Israeli attacks.  Zaman Al Wasl, a Syrian opposition media outlet, said Syrian air force commanders were trying to shut Iranian troops and Hizbollah fighters out of their air bases to try to shield the sites from Israeli strikes.  Potential cracks in the Russian-Iranian relationship have become increasingly visible in recent weeks.  Vladimir Putin, the Russian president, said in mid-May that all foreign forces would leave Syria once the Assad regime was fully in control of the country. The comments appeared to anger Iran. An Iranian foreign ministry spokesman said in response: “No one can make Iran do things; Iran has its own independent policies.” Sergei Lavrov, Russia’s foreign minister, also said Monday that only Syrian regime forces should be stationed on Syria’s southern border – implying that neither Iran nor Hizbollah should be allowed near the Israeli border. The comment appeared to be another small victory for Israel, which has long urged Russia in rein in Iran’s presence all across Syria but especially in the south near the Israeli border.  Syrian regime forces have captured significant territory from rebel forces in recent months Credit: LOUAI BESHARA/AFP/Getty Images Michael Horowitz, a senior analyst at the Le Beck geopolitical consultancy, said Israel had been trying for a long time to warn Russia about the dangers of Iran’s presence in Syria but had only recently gained traction.    “The Israeli strategy was always to convince Russia that they had a lot to lose if they didn’t do anything about Iran. Until a few weeks ago, I would have told you they were doing that in vain and that Russia didn’t understand and didn’t care. But it’s changed because the escalatory strategy of Israeli strikes in Syria is really threatening to trigger conflict,” he said.  Mr Horowitz cautioned that the recent shift did not mean Israel would necessarily achieve its goal of forcing Iran out of Syria. “This doesn’t mean Israel has won. But it means the dynamics are changing for the first time.”  Even if Russia and the Syrian regime do believe that Iran’s presence is coming at too high a price, it is not clear how they could force Iranian troops and their Shia militias allies out of Syria.  Iran has invested heavily in propping up the Assad regime during years of fighting and is not likely to give up its presence easily. Assad’s battered forces are also still heavily dependent on Iranian-controlled militias as they try to conquer the remaining pockets of rebel-held territory in Syria.  Russia has provided the air power to help the Assad regime, while Iran has provided much of the ground forces Credit: Photo by Marina Lystseva\TASS via Getty Images “Assad and the Russians still need the Shia militias to help them finish off what they have started Syria,” said Mr Tzuriel, the Israeli official. “That is part of the consideration and there is an issue of timing here. But that does not change my basic assessment that at the end of the day there is an opportunity now.” The US expressed alarm over the weekend that Syrian regime forces were massing for an assault on a rebel-held area in the southwest of the country, near the border with Jordan and the Israeli-occupied Golan Heights.  The area is part of a “de-escalation zone” where both Assad’s forces and rebel fighters are supposed to be observing a ceasefire. The agreement on the de-escalation zones were made last year between the US, Russia and Jordan.  Regime forces have launched attacks in de-escalation zones in other parts of Syria and met little protest from the US. But the southwestern zone is acutely sensitive because of its proximity to Jordan and Israel, both US allies.  The US warned that it would take “firm and appropriate measures” if Assad’s forces moved forward with the offensive. The Syrian regime has so far signaled it intends to move forward with the assault, despite American warnings. 


Source: Yahoo! News

James Harden says 'there's no pressure' on Rockets, calls Game 7 at home 'an opportunity'

  1. James Harden says ‘there’s no pressure’ on Rockets, calls Game 7 at home ‘an opportunity’  ESPN
  2. Houston Rockets star Chris Paul receiving treatment ‘around the clock’ on injured right hamstring  NBA.com
  3. Juggernaut Warriors show up late, put clamps down on Rockets to force Game 7  Yahoo Sports
  4. The Klay Thompson Game That Changed the Course of the NBA  Last Word on Pro Basketball (blog)
  5. NBA playoffs: Warriors dismantle Rockets in second half to force winner-take-all Game 7  Washington Post
  6. Full coverage


Source: Google News

The Royal Wedding was another perfect opportunity to troll Trump's inauguration

The Royal Wedding was another perfect opportunity to troll Trump's inaugurationThe Royal Wedding day was all about Prince Harry, Meghan Markle, and Donald Trump, of course. As massive crowds showed up to celebrate the couple’s big day, many couldn’t help but notice that more people seemed to crowding the streets of the post-wedding carriage procession through Windsor than were present at Donald Trump’s 2017 Inauguration. SEE ALSO: Google celebrates Meghan and Harry’s wedding with stunning Doodle Trump’s inaugural crowd size has been a running joke on the internet ever since former Press Secretary Sean Spicer dubbed Trump’s turnout “The largest audience to ever witness an inauguration — period — both in person and around the globe.” Then, to troll Trump, people began comparing scarcely populated photos of his inauguration to larger crowds at Obama’s, and the Women’s Marches, and so on.  To keep the tradition alive, people were sure to let Trump know thousands turned out to support the Royal Wedding. BBC Three threw shade by tweeting side-by-side photos of Trump’s crowd and Harry and Meghan’s with the casually bold caption, “just saying ¯_(ツ)_/¯.” just saying ¯_(ツ)_/¯ pic.twitter.com/1zoOGFKeU3 — BBC Three (@bbcthree) May 19, 2018 And even
Harry Potter author and known Trump basher, J.K. Rowling, got in on the fun. Love > Hate pic.twitter.com/iDzjmJ9qSt — J.K. Rowling (@jk_rowling) May 19, 2018 Other Twitter users followed suit, taking a short break from worshiping the beautiful bride and groom to make some classic American political memes. Dear @realDonaldTrumpTwo words…”Crowd size”Hey, at least you have Prince Harry beat on the number of weddings you’ve each had, right?#RoyalWeddingThanks @bbcthree pic.twitter.com/5UczwhzF9T — Brian Krassenstein (@krassenstein) May 19, 2018 Wow..the Royal wedding crowd…alot more than your inaugural 🤣🤣🤣 pic.twitter.com/AbUFClq846 — cla (@DayQuint) May 19, 2018 Trump will be secretly wondering if this royal wedding crowd is bigger than at his inauguration 😂 — Skye Robertson (@skyebird) May 19, 2018 My my the crowd size for #RoyalWedding2018 is bigger than Trump’s inauguration 😂 pic.twitter.com/rsdM3KMB2o — Fayza Khandoker (@FayzaKhandoker) May 19, 2018 I’m waiting for @seanspicer and @realDonaldTrump to come out and say the inauguration crowd was double that of the royal wedding. #ROYALWEDDING #MAGAts https://t.co/Uosdo4xBp9 — Sahin Dirilmis (@DrKingCantona) May 19, 2018 Since Trump and loyal Press Secretary Sean Spicer have parted ways, we’re not sure who will come to the defense of the president’s record-setting inauguration crowds now. Oh well, congrats Harry and Meghan on your yuge crowds! (And marriage, I guess.)
Want more clever culture writing beamed directly to your inbox? Sign up
here
for the twice-weekly Click Click Click newsletter. It’s fun – we promise. WATCH: Lifetime just released a movie about Prince Harry and Meghan Markle in honor of their upcoming wedding


Source: Yahoo! News

US engineering giant sees 'tremendous opportunity' in Saudi nuclear energy plans

  1. US engineering giant sees ‘tremendous opportunity’ in Saudi nuclear energy plans  CNBC
  2. Washington’s Plan for a Nuclear Agreement with Saudi Arabia May Be in Jeopardy  The National Interest Online
  3. Inside the Opening of Saudi Arabia’s First Movie Theater in 35 Years  VICE
  4. America’s inevitable war with Iran  The Week Magazine
  5. Full coverage


Source: Google News – Entertainment