Sucralose produces previously unidentified metabolites

Sucralose, a widely used artificial sweetener sold under the trade name Splenda®, is metabolized in the gut, producing at least two fat-soluble compounds, according to a recent study using rats. The finding differs from the studies used to garner regulatory approval for sucralose, which reported that the substance was not broken down in the body.
Source: Science Daily

A pretty plant of summer produces a promising anti-diabetes compound

Montbretin A (MbA), a natural compound with great potential for the treatment of type-2 diabetes, was discovered in the ornamental plant montbretia ten years ago, but it can’t be produced on a large scale until its biosynthesis is understood. Scientists have now discovered genes and enzymes responsible for MbA biosynthesis and demonstrated the potential for metabolic engineering of wild tobacco to produce this promising drug candidate.
Source: Science Daily

Hawaii's Kilauea Volcano produces two more explosions overnight

  1. Hawaii’s Kilauea Volcano produces two more explosions overnight  UPI.com
  2. Volcano Kilauea Has Created “New Land” With Its Lava  Inverse
  3. Steam explosion spreads ash fallout at Kīlauea summit nearly 40 days after initial eruption  AccuWeather.com
  4. Lava boils away largest lake on Big Island in about 90 minutes  SFGate
  5. Full coverage


Source: Google News

Chemical compound produces beneficial inflammation, remyelination that could help treat multiple sclerosis

Researchers report that indazole chloride, a synthetic compound that acts on one form of the body’s estrogen receptors, is able to remyelinate (add new myelin to) damaged axons and alter the body’s immune system — findings that could help treat multiple sclerosis. Drugs available to treat MS alter the immune system but do not induce repair of damaged axons.
Source: Science Daily

Engineered Chinese shrub produces high levels of antimalarial compound

Artemisinin is a potent antimalarial compound produced naturally in low amounts by the Chinese shrub Artemisia annua, commonly known as sweet wormwood. Researchers in China now report a high-quality draft genome sequence of A. annua and their use of this information along with gene expression data to metabolically engineer plant lines that produce high levels of artemisinin.
Source: Science Daily

Metal-organic compounds produces new class of glass

Lightning and volcanos both produce glass, and humans have been making glass from silicon dioxide since prehistory. Industrialization brought us boron-based glasses, polymer glasses and metallic glasses, but now an international team of researchers has developed a new family of glass based on metals and organic compounds that stacks up to the original silica in glass-forming ability.
Source: Science Daily